Science

In the gold-standard preclinical model, AURA cut bacteria a million‑fold.

Preclinical. A chronic wound infected with three ESKAPE pathogens, the bacteria best known for escaping antibiotics: Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii. AURA is an investigational product and is not approved for use in any country.

Peer-reviewed

Ultrasound is the switch that turns delivery into potency.

44.4×

less drug to eradicate mature biofilms

25.5×

less drug to eliminate dormant persister cells

11.1×

more antibiotic inside the bacteria

Published in npj Antimicrobials & Resistance, 2025.

Stress-tested

Tested against the toughest models. It held.

  • Against resistance

    It held after bacteria swapped resistance genes.

  • Beneath the surface

    It reached bacteria inside dense, necrotic tissue.

  • On the structure

    The biofilm’s architecture came apart.

  • Without rebound

    The effect deepened over time.

All in preclinical wound models. Unpublished data, AURApeutics.